Transabdominal Ultrasound and Magnetic Resonance Enterography in Inflammatory Bowel Disease: Results of an Observational Retrospective Single-Center Study

Lenika Calavrezos; Peter Bannas; Malte Warncke; Christiane Wiegard; Samuel Huber; Carolin Manthey

doi:10.1055/a-1781-4410

Transabdominal Ultrasound and Magnetic Resonance Enterography in Inflammatory Bowel Disease: Results of an Observational Retrospective Single-Center Study

Ultrasound Int Open. 2022 Sep 26;8(1):E22-E28. doi: 10.1055/a-1781-4410. eCollection 2022 Jan.

Authors

Lenika Calavrezos¹, Peter Bannas², Malte Warncke², Christiane Wiegard¹, Samuel Huber¹, Carolin Manthey¹

Affiliations

¹ Department of Internal Medicine and Gastroenterology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
² Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf Center for Diagnostics, Hamburg, Germany.

Abstract

Purpose Transabdominal ultrasound (US) and magnetic resonance enterography (MRE) are used to assess disease activity and extent in IBD, but their impact on therapeutic decisions is unclear. Therefore, our study has two goals: to compare the usefulness of US and MRE in assessing disease extent and activity in the small and large bowel, and to determine the relevance for clinical decisions in IBD. Materials and Methods We included 54 IBD patients who had undergone both MRE and US within three months. We used the construct reference standard model to compare MRE and US for detecting inflammation and examined the impact on clinical decisions in IBD patients. Results In 54 IBD patients (44 patients Crohn's disease (CD), 5 ulcerative colitis (UC), 5 indeterminate colitis (IC)), 42 patients (77.8%) showed inflammation either in the small or large bowel. Small bowel disease was present in 34 patients (77.3%). Complications were found in 19 patients (35.2%). MRE and US both showed high sensitivity (90.5 and 88.1%) and moderate specificity (50% in MRE and US) for detecting inflammation. MRE revealed higher sensitivity than US for detecting conglomerate tumors without statistical significance (85.7 vs. 71.4%, p=1.0) and equal specificity (97.9 vs 97.7, p=1.0). Therapeutic decisions included steroids in 20 patients (47.6%) and surgery/percutaneous drainage in six patients (14.3%), these decisions were triggered by results of US or MRE in equal distribution. Conclusion US and MRE have comparable sensitivity and specificity for detecting intestinal inflammation and complications in IBD patients. Therefore, both methods are sufficient for making clinical decisions.

Keywords: MR imaging; STRUCTURES & SYSTEMS; abdomen, AREAS; abscess; fistula, THEMES; inflammation.

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