Anthropometric parameters and radiation doses during percutaneous coronary procedures

Abstract

Purpose: Body size is a major determinant of patient's dose during percutaneous coronary interventions (PCI). Body mass index, body surface area (BSA), lean body mass and weight are commonly used estimates for body size. We aim to identify which of these measures and which procedural/clinical characteristics can better predict received dose.

Methods: Dose area product (DAP, Gycm²), fluoroscopy DAP rate (Gycm²/min), fluoroscopy DAP (Gycm²), cine-angiography DAP (Gycm²), Air Kerma (mGy) were selected as indices of patient radiation dose. Different clinical/procedural variables were analysed in multiple linear regression models with previously mentioned patient radiation dose parameters as end points. The best model for each of them was identified.

Results: Overall 6623 PCI were analysed, median fluoroscopy DAP rate was 35 [IQR 2.7,4.4] Gycm², median total DAP was 62.7 [IQR 38.1,107] Gycm². Among all anthropometric variables, BSA showed the best correlation with all radiation dose parameters considered. Every 1 m² increment in BSA added 4.861 Gycm²/min (95% CI [4.656, 5.067]) to fluoroscopy DAP rate and 164 Gycm² (95% CI [145.3, 182.8]) to total DAP. Height and female sex were significantly associated to a reduction in fluoroscopy DAP rate and total DAP. Coronary angioplasty, diabetes, basal creatinine and the number of treated vessels were associated to higher values.

Conclusions: Main determinants of patient radiation dose are: BSA, female sex, height and number of treated vessels. In an era of increasing PCI complexity and obesity prevalence, these results can help clinicians tailoring X-ray administration to patient's size.

Keywords: Body surface area; Coronary angiography; Dose area product; Radiation exposure.