The association of objectively and subjectively measured physical activity and sedentary time with prediabetes and type 2 diabetes in adults: a cross-sectional study in Framingham Heart Study cohorts

Appl Physiol Nutr Metab. 2022 Oct 1;47(10):1023-1030. doi: 10.1139/apnm-2022-0232. Epub 2022 Jul 25.

Abstract

The purpose of this study was to examine whether using both objectively (accelerometer) and subjectively (questionnaire) measured moderate- to vigorous-intensity physical activity (MVPA) and sedentary time (SED) improves the prediction of prediabetes and type 2 diabetes (pre/T2D) using data from the Framingham Heart Study (n = 4200). Logistic regression was used to examine the odds ratio of pre/T2D in groups cross-classified by subjective and objective MVPA and SED. Less than half of participants fell into concordant categories of MVPA and SED using subjective and objective measures, with 7.0%-9.4% of participants in the extreme discordant categories of high-low or low-high subjective-objective MVPA or SED. Low objective MVPA, regardless of subjective MVPA status, was associated with a higher prevalence of pre/T2D (P < 0.05). When cross-classifying by MVPA and SED, the majority of participants fell into concordant categories of MVPA-SED, with <4% of participants in the extreme discordant categories of MVPA-SED. Low objective MVPA, regardless of objective SED, was associated with a higher prevalence of pre/T2D (P < 0.05). These findings suggest that low objectively measured MVPA appears more closely associated with pre/T2D risk compared with subjective measures, and there does not appear to be an additive effect of SED on pre/T2D risk after accounting for MVPA.

Keywords: accelerometer; accéléromètre; activité physique; diabète de type 2; physical activity; prediabetes; prédiabète; questionnaire; sedentary time; temps de sédentarité; type 2 diabetes.

MeSH terms

  • Accelerometry
  • Adult
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2* / epidemiology
  • Exercise
  • Humans
  • Longitudinal Studies
  • Motor Activity
  • Prediabetic State* / epidemiology
  • Sedentary Behavior