Linking and unlinking the paediatric brain: age-invariant neural correlates of general anaesthesia

Michael P Puglia 2nd; George A Mashour

doi:10.1016/j.bja.2022.06.015

Linking and unlinking the paediatric brain: age-invariant neural correlates of general anaesthesia

Br J Anaesth. 2023 Feb;130(2):e215-e216. doi: 10.1016/j.bja.2022.06.015. Epub 2022 Jul 19.

Authors

Michael P Puglia 2nd¹, George A Mashour²

Affiliations

¹ Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, USA; Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: MPuglia@med.umich.edu.
² Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, USA; Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI, USA; Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, MI, USA.

PMID: 35863952
DOI: 10.1016/j.bja.2022.06.015

Abstract

There is no single electroencephalographic metric for general anaesthesia that is validated for both children and adults. This is, in part, because of the changing electroencephalographic features associated with development. Here, we discuss how alterations in correlated brain activity during general anaesthesia advance our understanding of anaesthetic monitoring and the neurobiology of consciousness.

Keywords: brain monitoring; delta bandwidth; electroencephalography; functional connectivity; graph theory; paediatric anaesthesia.

Publication types

Editorial
Comment

MeSH terms

Adult
Anesthesia, General*
Brain*
Child
Consciousness
Electroencephalography
Humans