Malignant hyperthermia in Czechia and Slovakia

Martina Klincová; Dagmar Štěpánková; Ivana Schröderová; Eva Klabusayová; Edita Ošťádalová; Iveta Valášková; Lenka Fajkusová; Jana Zídková; Renata Gaillyová; Petr Štourač

doi:10.1016/j.bja.2022.04.029

Malignant hyperthermia in Czechia and Slovakia

Br J Anaesth. 2022 Aug;129(2):e41-e43. doi: 10.1016/j.bja.2022.04.029. Epub 2022 Jun 17.

Affiliations

¹ Department of Paediatric Anaesthesiology and Intensive Care Medicine, University Hospital Brno, Brno, Czech Republic; Faculty of Medicine, Masaryk University, Brno, Czech Republic; Academic Centre for Malignant Hyperthermia of Masaryk University, Brno, Czech Republic.
² Department of Paediatric Anaesthesiology and Intensive Care Medicine, University Hospital Brno, Brno, Czech Republic; Faculty of Medicine, Masaryk University, Brno, Czech Republic; Academic Centre for Malignant Hyperthermia of Masaryk University, Brno, Czech Republic; Department of Simulation Medicine, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
³ Faculty of Medicine, Masaryk University, Brno, Czech Republic; Academic Centre for Malignant Hyperthermia of Masaryk University, Brno, Czech Republic; Department of Anaesthesiology and Intensive Care, St Anne's University Hospital, Brno, Czech Republic.
⁴ Department of Paediatric Anaesthesiology and Intensive Care Medicine, University Hospital Brno, Brno, Czech Republic; Faculty of Medicine, Masaryk University, Brno, Czech Republic.
⁵ Faculty of Medicine, Masaryk University, Brno, Czech Republic; Centre for Molecular Biology and Genetics, University Hospital Brno, Brno, Czech Republic.
⁶ Faculty of Medicine, Masaryk University, Brno, Czech Republic; Academic Centre for Malignant Hyperthermia of Masaryk University, Brno, Czech Republic; Centre for Molecular Biology and Genetics, University Hospital Brno, Brno, Czech Republic.
⁷ Institute of Medical Genetics and Genomics, University Hospital Brno, Brno, Czech Republic.
⁸ Department of Paediatric Anaesthesiology and Intensive Care Medicine, University Hospital Brno, Brno, Czech Republic; Faculty of Medicine, Masaryk University, Brno, Czech Republic; Academic Centre for Malignant Hyperthermia of Masaryk University, Brno, Czech Republic; Department of Simulation Medicine, Faculty of Medicine, Masaryk University, Brno, Czech Republic. Electronic address: petr.stourac@gmail.com.

PMID: 35718563
DOI: 10.1016/j.bja.2022.04.029

No abstract available

Keywords: CACNA1S; RYR1; STAC3; Slavic; invitro contraction test; malignant hyperthermia; pathogenic variant.

Publication types

Letter

MeSH terms

Calcium Channels, L-Type
Czech Republic
Humans
Malignant Hyperthermia* / therapy
Mutation
Ryanodine Receptor Calcium Release Channel / genetics
Slovakia / epidemiology

Substances

Calcium Channels, L-Type
Ryanodine Receptor Calcium Release Channel