kc-hits: a tool to aid in the evaluation and classification of chemical carcinogens

Bioinformatics. 2022 May 13;38(10):2961-2962. doi: 10.1093/bioinformatics/btac189.

Abstract

Motivation: The evaluation of chemicals for their carcinogenic hazard requires the analysis of a wide range of data and the characterization of these results relative to the key characteristics of carcinogens. The workflow used historically requires many manual steps that are labor-intensive and can introduce errors, bias and inconsistencies.

Results: The automation of parts of the evaluation workflow using the kc-hits software has led to significant improvements in process efficiency, as well as more consistent and comprehensive results.

Availability and implementation: https://gitlab.com/i1650/kc-hits.git.

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Automation
  • Carcinogens* / toxicity
  • Software*
  • Workflow

Substances

  • Carcinogens