Isolation of Specialized Plant Cells by Fluorescence-Activated Cell Sorting

Methods Mol Biol. 2022:2469:193-200. doi: 10.1007/978-1-0716-2185-1_16.

Abstract

Plant organs are built of different cell types, characterized by specific transcription programs and metabolic profiles. The possibility of isolation of such cell types to perform differential transcriptomic, proteomic and metabolomic analyses is highly important to understand many aspects of plant physiology, namely, the structure and regulation of economically valuable specialized metabolic pathways. Here, we describe the isolation of idioblast leaf protoplasts of the medicinal plant Catharanthus roseus by fluorescence-activated cell sorting, taking advantage of the differential autofluorescence properties of those specialized cells.

Keywords: Alkaloid metabolism; Autofluorescence; Catharanthus roseus; FACS; Idioblasts; Mesophyll; Plant cells; Protoplasts.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catharanthus*
  • Flow Cytometry
  • Gene Expression Regulation, Plant
  • Plant Cells* / metabolism
  • Plant Leaves / metabolism
  • Plant Proteins / metabolism
  • Proteomics

Substances

  • Plant Proteins