Pulmonary aspergillosis and cryptococcosis as a complication of COVID-19

Edward C Traver; Melanie Malavé Sánchez

doi:10.1016/j.mmcr.2022.01.003

Pulmonary aspergillosis and cryptococcosis as a complication of COVID-19

Med Mycol Case Rep. 2022 Mar:35:22-25. doi: 10.1016/j.mmcr.2022.01.003. Epub 2022 Jan 6.

Authors

Edward C Traver¹, Melanie Malavé Sánchez²

Affiliations

¹ University of Maryland Medical Center, Division of Infectious Diseases, Baltimore, 21201, USA.
² University of Maryland School of Medicine, Division of Infectious Disease, Baltimore, 21201, USA.

Abstract

Invasive fungal infections may complicate infection by SARS-CoV-2 and increase morbidity and mortality. A 59-year-old man with multiple medical comorbidities was transferred to our hospital for worsening hypoxic respiratory failure due to COVID-19 and received high-dose corticosteroids and 2 doses of cyclophosphamide. He was diagnosed with pulmonary aspergillosis and cryptococcosis by culture of a bronchoalveolar lavage sample. This patient's secondary infections were likely due to treatment with immunosuppressants, his comorbidities, and his prolonged critical illness.

Keywords: Aspergillus; CAPA; COVID-19; Cryptococcus; SARS-CoV-2.

Publication types

Case Reports

Grants and funding

K12 HL143886/HL/NHLBI NIH HHS/United States