Effect of graphite oxide and exfoliated graphite oxide as a modifier for the voltametric determination of dopamine in presence of uric acid and folic acid

H Vidya; B E Kumara Swamy; S C Sharma; G K Jayaprakash; S A Hariprasad

doi:10.1038/s41598-021-01328-w

Effect of graphite oxide and exfoliated graphite oxide as a modifier for the voltametric determination of dopamine in presence of uric acid and folic acid

Sci Rep. 2021 Dec 15;11(1):24040. doi: 10.1038/s41598-021-01328-w.

Authors

H Vidya¹, B E Kumara Swamy², S C Sharma^{3

4}, G K Jayaprakash⁵, S A Hariprasad⁶

Affiliations

¹ Department of P. G. Studies and Research in Industrial Chemistry, Kuvempu University, Jnanasahyadri, Shankaraghatta, Shimoga, Karnataka, 577 451, India.
² Department of P. G. Studies and Research in Industrial Chemistry, Kuvempu University, Jnanasahyadri, Shankaraghatta, Shimoga, Karnataka, 577 451, India. bek@kuvempu.ac.in.
³ National Assessment and Accreditation Council, Jain University, Bangalore, Karnataka, 560 069, India. scsharma.bangalore@gmail.com.
⁴ School of Energy Science and Engineering, Indian Institute of Technology Guwahati, Guwahati, 781039, India. scsharma.bangalore@gmail.com.
⁵ School of Advanced Chemical Sciences, Shoolini University, Bajhol, Himachal Pradesh, 173229, India.
⁶ Jain University, Bangalore, Karnataka, 560 069, India.

Abstract

In the present work, exfoliated graphite oxide (E-GO) was prepared by sonicating graphite oxide (GO) (prepared by modified Hummer's and Offemam methods). Prepared GO and E-GO were characterized using infrared absorption spectroscopy, X-ray diffraction, and scanning electron microscopy. The electrocatalytic properties of GO and E-GO towards detection of dopamine (DA), uric acid (UA), and folic acid (FA) were investigated using cyclic voltammetry and differential pulse voltammetry. Our results revealed that E-GO has a slighter advantage over the GO as an electrode modifier for detection DA, UA, and FA, which might be ascribed to the good conductivity of E-GO when compared to the GO.