Endothelial Progenitor Cells: An Appraisal of Relevant Data from Bench to Bedside

Int J Mol Sci. 2021 Nov 28;22(23):12874. doi: 10.3390/ijms222312874.

Abstract

The mobilization of endothelial progenitor cells (EPCs) into circulation from bone marrow is well known to be present in several clinical settings, including acute coronary syndrome, heart failure, diabetes and peripheral vascular disease. The aim of this review was to explore the current literature focusing on the great opportunity that EPCs can have in terms of regenerative medicine.

Keywords: EPC; ischemic heart disease; progenitor cells.

Publication types

  • Review

MeSH terms

  • Animals
  • Cardiovascular Diseases / physiopathology
  • Cell Separation
  • Endothelial Progenitor Cells / physiology*
  • Humans