Functionalized MoS2 Nanoflowers with Excellent Near-Infrared Photothermal Activities for Scavenging of Antibiotic Resistant Bacteria

Lulu Liu; Wanfeng Wu; Yan Fang; Haoqiang Liu; Fei Chen; Minwei Zhang; Yanan Qin

doi:10.3390/nano11112829

Functionalized MoS₂ Nanoflowers with Excellent Near-Infrared Photothermal Activities for Scavenging of Antibiotic Resistant Bacteria

Nanomaterials (Basel). 2021 Oct 25;11(11):2829. doi: 10.3390/nano11112829.

Authors

Lulu Liu^{1

2}, Wanfeng Wu^{1

2}, Yan Fang^{1

2}, Haoqiang Liu^{1

2}, Fei Chen^{1

2}, Minwei Zhang^{1

2}, Yanan Qin^{1

2}

Affiliations

¹ College of Life Science & Technology, Xinjiang University, Urumqi 830046, China.
² Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, Urumqi 830046, China.

Abstract

Presently, antibiotic resistant bacteria (ARB) have been commonly found in environment, such as air, soil and lakes. Therefore, it is urgent and necessary to prepare antimicrobial agents with excellent anti-antibiotic resistant bacteria. In our research, poly-ethylene glycol functionalized molybdenum disulfide nanoflowers (PEG-MoS₂ NFs) were synthesized via a one-step hydrothermal method. As-prepared PEG-MoS₂ NFs displayed excellent photothermal conversion efficiency (30.6%) and photothermal stability. Under 808 nm NIR laser irradiation for 10 min, the inhibition rate of tetracycline-resistant Bacillus tropicalis and Stenotrophomonas malphilia reached more than 95% at the concentration of 50 μg/mL. More interestingly, the photothermal effect of PEG-MoS₂ NFs could accelerate the oxidation of glutathione, resulting in the rapid death of bacteria. A functionalized PEG-MoS₂ NFs photothermal anti-antibiotic resistant system was constructed successfully.

Keywords: MoS2 nanoflowers; antibacterial; antibiotics resistant bacteria.