Defibrotide for Sinusoidal Obstruction Syndrome and Nodular Regenerative Hyperplasia After Oxaliplatin-Based Hepatic Intra-Arterial Chemotherapy: A Case Report

Clin Colorectal Cancer. 2022 Jun;21(2):e98-e101. doi: 10.1016/j.clcc.2021.10.003. Epub 2021 Oct 16.

Authors

Amaury Druet¹, Jean-François Mosnier², Erwan Corbineau³, Tamara Matysiak-Budnik¹, Yann Touchefeu⁴, Caroline Viala¹

Affiliations

¹ Institut des Maladies de l'Appareil Digestif, Digestive Oncology Unit, University Hospital, Nantes, France.
² Department of Pathology, University Hospital, Nantes, France.
³ Department of Pharmacy, University Hospital, Nantes, France.
⁴ Institut des Maladies de l'Appareil Digestif, Digestive Oncology Unit, University Hospital, Nantes, France. Electronic address: yann.touchefeu@chu-nantes.fr.

PMID: 34776359
DOI: 10.1016/j.clcc.2021.10.003

No abstract available

Keywords: Colorectal neoplasm; Defibrotide; Intra-arterial infusion; Oxaliplatin; Sinusoidal obstruction syndrome.

Publication types

Case Reports

MeSH terms

Colorectal Neoplasms* / complications
Hepatic Veno-Occlusive Disease* / chemically induced
Hepatic Veno-Occlusive Disease* / diagnosis
Hepatic Veno-Occlusive Disease* / drug therapy
Humans
Hyperplasia / complications
Oxaliplatin / adverse effects
Polydeoxyribonucleotides

Substances

Polydeoxyribonucleotides
Oxaliplatin
defibrotide