Monoamine Oxidases Desensitize Intracellular β1AR Signaling in Heart Failure

Circ Res. 2021 Oct 29;129(10):965-967. doi: 10.1161/CIRCRESAHA.121.319546. Epub 2021 Sep 17.
No abstract available

Keywords: catecholamine; epinephrine; heart failure; phosphorylation; sarcoplasmic reticulum.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Cells, Cultured
  • Heart Failure / metabolism*
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Monoamine Oxidase / metabolism*
  • Myocytes, Cardiac / metabolism
  • Receptors, Adrenergic, beta-1 / metabolism*
  • Sarcoplasmic Reticulum Calcium-Transporting ATPases / metabolism
  • Signal Transduction

Substances

  • Receptors, Adrenergic, beta-1
  • Monoamine Oxidase
  • Sarcoplasmic Reticulum Calcium-Transporting ATPases