Household level SARS-CoV-2 sero-epidemiology in a high prevalence group of adults and children-implications for community infection control

Alan Werzberger; Juan Manuel Carreño; Sinai Serocore Team; Adam Polinger; Florian Krammer; Philip Zachariah

doi:10.1016/j.ajic.2021.08.015

Household level SARS-CoV-2 sero-epidemiology in a high prevalence group of adults and children-implications for community infection control

Am J Infect Control. 2021 Nov;49(11):1438-1440. doi: 10.1016/j.ajic.2021.08.015. Epub 2021 Aug 20.

Authors

Alan Werzberger¹, Juan Manuel Carreño², Sinai Serocore Team³, Adam Polinger⁴, Florian Krammer³, Philip Zachariah⁵

Affiliations

¹ Best Health Care, Monroe, NY; Department of Pediatrics, Columbia University Irving Medical Center, New York, NY.
² Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY.
³ Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY.
⁴ Ezras Choilim Health Center, Monroe, NY.
⁵ Department of Pediatrics, Columbia University Irving Medical Center, New York, NY. Electronic address: pz2177@cumc.columbia.edu.

Abstract

In 108 households (n = 474, 280 ≤ 18 years old), SARS-CoV-2 seroprevalence was significantly associated with age (range 37.5%-78.7%) and lowest in children ≤ 10 years old. Among 92 households with members ≤ 18, 14 (15.2%) had only a seropositive child or adolescent, while 16 (17.4%) had only seropositive adults. Households with both groups concurrently seropositive (n = 62) were larger in size (mean 8.11 ± 2.49) vs (mean 5.77 ± 2.31) (P < .001).

Keywords: COVID-19; Children; Household.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Adolescent
Adult
Antibodies, Viral
COVID-19*
Child
Humans
Infection Control
Prevalence
SARS-CoV-2*
Seroepidemiologic Studies

Substances

Antibodies, Viral

Abstract

Publication types

MeSH terms

Substances

Grants and funding