Visuomotor control in mice and primates

E J Tehovnik; E Froudarakis; F Scala; S M Smirnakis; S S Patel; A S Tolias

doi:10.1016/j.neubiorev.2021.08.009

Visuomotor control in mice and primates

Neurosci Biobehav Rev. 2021 Nov:130:185-200. doi: 10.1016/j.neubiorev.2021.08.009. Epub 2021 Aug 17.

Authors

E J Tehovnik¹, E Froudarakis², F Scala³, S M Smirnakis⁴, S S Patel³, A S Tolias⁵

Affiliations

¹ Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA; Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX, USA. Electronic address: tehovnikej@gmail.com.
² Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Heraklion, Greece.
³ Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA; Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX, USA.
⁴ Department of Neurology, Brigham and Women's Hospital and Jamaica Plain Veterans Administration Hospital, Harvard Medical School, Boston, MA, USA.
⁵ Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA; Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX, USA; Department of Electrical Engineering and Computer Engineering, Rice University, Houston, TX, USA.

Abstract

We conduct a comparative evaluation of the visual systems from the retina to the muscles of the mouse and the macaque monkey noting the differences and similarities between these two species. The topics covered include (1) visual-field overlap, (2) visual spatial resolution, (3) V1 cortical point-image [i.e., V1 tissue dedicated to analyzing a unit receptive field], (4) object versus motion encoding, (5) oculomotor range, (6) eye, head, and body movement coordination, and (7) neocortical and cerebellar function. We also discuss blindsight in rodents and primates which provides insights on how the neocortex mediates conscious vision in these species. This review is timely because the field of visuomotor neurophysiology is expanding beyond the macaque monkey to include the mouse; there is therefore a need for a comparative analysis between these two species on how the brain generates visuomotor responses.

Keywords: Blindsight; Cerebellum; Cortical point-image; Macaque monkey; Motion; Mouse; Neocortex; Objects; Oculomotor range.

Publication types

Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Animals
Eye Movements*
Mice
Motion Perception*
Primates
Retina
Vision, Ocular

Abstract

Publication types

MeSH terms

Grants and funding