Sleep-Disordered Breathing and Cardiovascular Disease in Children and Adolescents: A Scientific Statement From the American Heart Association

J Am Heart Assoc. 2021 Sep 21;10(18):e022427. doi: 10.1161/JAHA.121.022427. Epub 2021 Aug 18.

Abstract

Obstructive sleep apnea (OSA) is a known risk factor for cardiovascular disease in adults. It is associated with incident systemic hypertension, arrhythmia, stroke, coronary artery disease, and heart failure. OSA is common in children and adolescents, but there has been less focus on OSA as a primary risk factor for cardiovascular disease in children and adolescents. This scientific statement summarizes what is known regarding the impact of sleep-disordered breathing and, in particular, OSA on the cardiovascular health of children and adolescents. This statement highlights what is known regarding the impact of OSA on the risk for hypertension, arrhythmia, abnormal ventricular morphology, impaired ventricular contractility, and elevated right heart pressure among children and adolescents. This scientific statement also summarizes current best practices for the diagnosis and evaluation of cardiovascular disease-related complications of OSA in children and adolescents with sleep apnea and highlights potential future research in the area of sleep-disordered breathing and cardiovascular health during childhood and adolescence.

Keywords: AHA Scientific Statements; arrhythmia; cardiovascular disease; left ventricular hypertrophy; obstructive sleep apnea; pediatric; sleep‐disordered breathing; systemic hypertension.

MeSH terms

  • Adolescent
  • American Heart Association
  • Cardiovascular Diseases* / epidemiology
  • Child
  • Heart Disease Risk Factors
  • Humans
  • Sleep Apnea, Obstructive* / epidemiology
  • United States / epidemiology