Antibiotic therapy in children with community-acquired pneumonia

Acta Paediatr. 2021 Dec;110(12):3246-3250. doi: 10.1111/apa.16030. Epub 2021 Jul 23.

Abstract

PubMed was reviewed on antibiotic treatment of community-acquired pneumonia (CAP) in children for the years 2011-2020, and three clinical trials in high-income and eight in low-income countries were found. Prospective studies combining laboratory and clinical findings for steering of antibiotic treatment found that five-day courses were equally effective as longer courses. No new antibiotics were launched for children's CAP during the last 10 years. Five-day courses are equally effective as 7- to 10-day courses for CAP in children. Stewardship of antibiotics needs lessening of exposure to antibiotics by better targeting their use and by shortening the lengths of antibiotic courses.

Keywords: antibiotics; community-acquired pneumonia; evidence-based guidelines; treatment.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Community-Acquired Infections* / drug therapy
  • Humans
  • Pneumonia* / drug therapy
  • Prospective Studies

Substances

  • Anti-Bacterial Agents