Low Prevalence of Severe Underlying Pathology in Children With Recurrent Respiratory Tract Infections

Daphne Peeters; Pieter Verhulst; Anja Aph Vaessen-Verberne; Xandra W van den Tweel; Jeroen G Noordzij; Gertjan J A Driessen

doi:10.1097/INF.0000000000003256

Low Prevalence of Severe Underlying Pathology in Children With Recurrent Respiratory Tract Infections

Pediatr Infect Dis J. 2021 Nov 1;40(11):e424-e426. doi: 10.1097/INF.0000000000003256.

Authors

Daphne Peeters¹, Pieter Verhulst², Anja Aph Vaessen-Verberne³, Xandra W van den Tweel⁴, Jeroen G Noordzij⁵, Gertjan J A Driessen^{1

6}

Affiliations

¹ From the Juliana Children's Hospital, pediatric department, the Hague, the Netherlands.
² Radboudumc, pediatric department, Nijmegen, the Netherlands.
³ Amphia hospital, pediatric department, Breda, the Netherlands.
⁴ Maasstad hospital, pediatric department, Rotterdam, the Netherlands.
⁵ Reinier de Graaf hospital, pediatric department, Delft, the Netherlands.
⁶ Maastricht University Medical Center+ (MUMC+), Maastricht, the Netherlands.

PMID: 34260493
DOI: 10.1097/INF.0000000000003256

Abstract

No underlying pathology could be detected in 64% of 208 children presenting with recurrent respiratory tract infections in general pediatric practice. Asthma/preschool wheezing and adenoid hypertrophy were commonly diagnosed. None of the children had a severe primary immunodeficiency or severe pulmonary illness such as cystic fibrosis. Our findings can guide pediatricians in their diagnostic approach of children with respiratory tract infections.

Publication types

Observational Study

MeSH terms

Adolescent
Asthma / epidemiology
Child
Child, Preschool
Female
Humans
Infant
Male
Prevalence
Reinfection / diagnosis
Reinfection / epidemiology*
Reinfection / pathology
Respiratory Sounds / etiology
Respiratory Tract Infections / diagnosis
Respiratory Tract Infections / epidemiology*
Respiratory Tract Infections / pathology*
Retrospective Studies
Risk Factors