Prevalence and approaches to manage iron deficiency anemia (IDA)

Crit Rev Food Sci Nutr. 2022;62(32):8815-8828. doi: 10.1080/10408398.2021.1935442. Epub 2021 Jun 7.

Abstract

Iron is a vital micronutrient required for growth and development at all stages of human life. Its deficiency is the primary cause of anemia that poses a significant global health problem and challenge for developing countries. Various risks are involved during iron deficiency anemia (IDA), such as premature delivery, low birth weight, etc. Further, it affects children's cognitive functioning, delays motor development, hampers physical performance and quality of life. It also speeds up the morbidity and mortality rate among women. The major reasons accountable are elevated iron demand in diet, socio-economic status, and disease condition. Various strategies have been adopted to reduce the IDA occurrence, such as iron supplementation, iron fortificants salts, agronomic practices, dietary diversification, biofortification, disease control measures, and nutritional education. Usually, the staple food groups for fortification are considered, but the selection of food fortificants and their combination must be safe for the consumers and not alter the finished product's stability and acceptability. Genetically modified breeding practices also increase the micronutrient levels of cereal crops. Therefore, multiple strategies could be relied on to combat IDA.

Keywords: Absorption; anemia; bioavailability; dietary diversification; fortification.

MeSH terms

  • Anemia*
  • Anemia, Iron-Deficiency* / epidemiology
  • Anemia, Iron-Deficiency* / prevention & control
  • Child
  • Female
  • Food, Fortified
  • Humans
  • Iron
  • Iron Deficiencies*
  • Micronutrients
  • Prevalence
  • Quality of Life

Substances

  • Iron
  • Micronutrients