68Ga-DOTATATE and 68Ga-NODAGA-JR11 PET/CT Images in a Patient With Gastric Neuroendocrine Tumor

Clin Nucl Med. 2021 Oct 1;46(10):853-855. doi: 10.1097/RLU.0000000000003732.

Abstract

A 52-year-old man with newly diagnosed gastric neuroendocrine tumor (NET) underwent 68Ga-NODAGA-JR11 and 68Ga-DOTATATE imaging. 68Ga-DOTATATE PET/CT showed no 68Ga-DOTATATE uptake in the lesion, where 68Ga-NODAGA-JR11 showed intense uptake. The patient subsequently received endoscopic submucosal dissection and en bloc resection of the lesion, which was pathologically confirmed as gastric NET (G2). The positive findings of 68Ga-NODAGA-JR11 in the current case highlighted that 68Ga-NODAGA-JR11 PET/CT may be a promising molecular imaging technique for the detection of NETs with high sensitivity.

Publication types

  • Case Reports

MeSH terms

  • Acetates
  • Heterocyclic Compounds, 1-Ring
  • Humans
  • Male
  • Middle Aged
  • Neuroendocrine Tumors* / diagnostic imaging
  • Organometallic Compounds*
  • Positron Emission Tomography Computed Tomography

Substances

  • 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane
  • Acetates
  • Heterocyclic Compounds, 1-Ring
  • Organometallic Compounds
  • gallium Ga 68 dotatate