Anti AChR antibody: relevance to diagnosis and clinical aspects of myasthenia gravis

Ital J Neurol Sci. 1988 Apr;9(2):141-5. doi: 10.1007/BF02337460.

Abstract

227 sera from myasthenic patients were tested for the presence of anti-AChR antibodies (anti-AChR Abs) by mean of a fetal calf receptor (Fc-AChR); 73.5% of cases proved positive with this method. Significant correlations were found between presence of anti-Fc-AChr Abs and various clinical aspects such as: clinical stage and duration of disease; moreover significantly higher than the median titers were found among younger patients (i.e. age less than 40 yrs).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Autoantibodies / analysis*
  • Humans
  • Immunologic Tests
  • Myasthenia Gravis / diagnosis*
  • Myasthenia Gravis / immunology
  • Receptors, Cholinergic / immunology*

Substances

  • Autoantibodies
  • Receptors, Cholinergic