Effectiveness of ibrutinib as first-line therapy for chronic lymphocytic leukemia patients and indirect comparison with rituximab-bendamustine: Results of study on 486 cases outside clinical trials

Affiliations

• ¹ Biothecnology Research Unit, AO of Cosenza, Cosenza, Italy.
• ² Hematology and Bone Marrow Transplant Unit, Hemato-Oncology Department, Augusta Victoria Hospital, East Jerusalem, Israel.
• ³ CNR-IFC, Research Unit of Reggio Calabria, Reggio Calabria, Italy.
• ⁴ Division of Hematology, S. Eugenio Hospital and University of Tor Vergata, Rome, Italy.
• ⁵ Hematology, Department of Translational and Precision Medicine, 'Sapienza' University, Rome, Italy.
• ⁶ Ematologia, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.
• ⁷ Centro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, Italy.
• ⁸ Fondazione Universitaria Policlinico A Gemelli di Roma, Rome, Italy.
• ⁹ Division of Hematology, A.O.U. Città della Salute e della Scienza di Torino, Torino, Italy.
• ¹⁰ Sourasky Medical Center, Institute of Hematology, and Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
• ¹¹ Division of Haematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
• ¹² Hematology and Stem Cell Transplantation Unit, Ospedale A. Businco, Cagliari, Italy.
• ¹³ Division of Hematology, Policlinico, Department of Surgery and Medical Specialties, University of Catania, Catania, Italy.
• ¹⁴ Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy.
• ¹⁵ Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
• ¹⁶ Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy.
• ¹⁷ Division of Hematology, Azienda Ospedaliera SS Arrigo e Biagio e Cesare Arrigo, Alessandria, Italy.
• ¹⁸ Hematology and Cell Therapy Unit, IRCCS-Istituto Tumori 'Giovanni Paolo II', Bari, Italy.
• ¹⁹ Hematology Department, G. Garibaldi Hospital, Catania, Italy.
• ²⁰ Clinica di Ematologia Ospedali Riuniti, Ancona, Italy.
• ²¹ Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
• ²² Hematology Unit AO of Cosenza, Cosenza, Italy.
• ²³ Section of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
• ²⁴ UOSD Ematologia ASL Roma 1, Roma, Italy.
• ²⁵ Reparto di Oncoematologia Azienda Ospedaliera Santa Maria di Terni, Terni, Italy.
• ²⁶ Mutagenesis and Cancer Prevention Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
• ²⁷ Clinica Ematologica, Centro Trapianti e Terapie Cellulari "Carlo Melzi", Azienda Sanitaria Universitaria Integrata di Udine, Udine, Italy.
• ²⁸ Molecular Pathology Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
• ²⁹ Hematology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
• ³⁰ Department of Hematology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
• ³¹ Department of Experimental Medicine, University of Genoa, Genoa, Italy.