Epilepsy surgery in COVID times-a unique conundrum

Childs Nerv Syst. 2021 Oct;37(10):3219-3224. doi: 10.1007/s00381-021-05048-4. Epub 2021 Apr 10.

Abstract

The COVID-19 pandemic has forced hospitals to prioritize admissions. Epilepsy surgeries have been postponed at most centers. As the pandemic continues with no definite end in sight in the near future, the question arises until when such patients should be denied appropriate treatment. A 12-year-old child with left-sided Rasmussen's encephalitis with drug refractory epilepsy (DRE) presented at the height of the pandemic, with worsening of seizure frequency from 4-5/day to 20/day, with new-onset epilepsia partialis continua. She demonstrated features of progressive cognitive decline. The pros and cons of operating during the pandemic were discussed with the parents by a multidisciplinary team. She underwent endoscopic left hemispherotomy. Postoperatively she became seizure free but developed hospital-acquired mild COVID infection for which she was treated accordingly. Chosen cases of severe DRE, as the one illustrated above, who are deemed to benefit from surgery by a multidisciplinary team of physicians, should be re-categorized into the most severe class of patients and scheduled for surgery as soon as possible. The risk benefit ratio of the seizures being mitigated by surgery on one hand and possibility of acquiring COVID infection during hospital stay has to be balanced and a decision made accordingly.

Keywords: Coronavirus; Drug refractory epilepsy; Endoscopic hemispherotomy; Infection.

MeSH terms

  • COVID-19*
  • Child
  • Epilepsy* / surgery
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Pandemics
  • SARS-CoV-2