Are microplastic particles a hotspot for the spread and the persistence of antibiotic resistance in aquatic systems?

Abstract

In the last decade, the study of the origin and fate of plastic debris received great attention, leading to a new and broad awareness of the hazard represented by these particles for the environment and the biota. At the same time, the scientific consideration on the leading role of the environment regarding the spread of antibiotic resistant bacteria (ARB) increased. Both, microplastic particles (MPs) and ARB share pollution sources and, in aquatic systems, MPs could act as a novel ecological niche, favouring the survival of pathogens and ARB. MPs can host a specific microbial biofilm, referred to as plastisphere, phylogenetically different from the surrounding planktonic microbial community and from the biofilm growing on other suspended particles. The plastisphere can influence the overall microbiome of a specific habitat, by introducing and supporting different species and by increasing horizontal gene transfer. In this review we collect and analyse the available studies coupling MPs and antibiotic resistance in water, highlighting knowledge gaps to be filled in order to understand if MPs could effectively act as a carrier of ARB and antibiotic resistance genes, and pose a real threat to human health.

Keywords: Antibiotic resistance; Microplastic; One-health; Plastisphere.