Bamboo Nodes as an Autoimmune Disease Laryngeal Manifestation. Case Series

J Voice. 2023 Jul;37(4):636.e1-636.e5. doi: 10.1016/j.jvoice.2021.02.020. Epub 2021 Mar 17.

Abstract

Introduction: Bamboo nodes are transverse creamy-yellow subepithelial nodes in the vocal folds (VF) midpoint, usually bilateral, resembling a bamboo stem. They appear almost exclusively in females, and are associated with underlying autoimmune diseases.

Case summary: Six female patients, 45.5 years median age, with underlying autoimmune diseases, consulted due to dysphonia. The laryngeal stroboscopy showed bilateral VF bamboo nodes in four patients, and unilateral in the remaining two. VF mobility was normal in all patients, while the mucosal wave was impaired in four of them. Treatment with speech therapy and proton pump inhibitors was indicated. All the patients were referred for rheumatologic evaluation and immunosuppressive treatment optimization. Follow-up in five patients showed vocal function self-perception and GRBAS scores improvement.

Discussion: VF bamboo nodes are an infrequent cause for dysphonia, associated with phonotrauma and autoimmune diseases. Speech therapy and a rheumatologic workup must be indicated, for immunosuppressive treatment enhancement.

Keywords: Dysphonia–Vocal fold–Bamboo nodes–Autoimmune disease–Laryngeal disorders.

Publication types

  • Review

MeSH terms

  • Arthritis, Rheumatoid* / complications
  • Autoimmune Diseases* / complications
  • Autoimmune Diseases* / diagnosis
  • Autoimmune Diseases* / therapy
  • Dysphonia* / diagnosis
  • Dysphonia* / etiology
  • Dysphonia* / therapy
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Laryngeal Diseases* / diagnosis
  • Laryngeal Diseases* / etiology
  • Laryngeal Diseases* / therapy
  • Vocal Cords

Substances

  • Immunosuppressive Agents