Resting-state functional network models for posttraumatic stress disorder

J Neurophysiol. 2021 Mar 1;125(3):824-827. doi: 10.1152/jn.00705.2020. Epub 2021 Feb 10.

Abstract

Four recent articles were examined for their use of resting-state functional magnetic resonance imaging on participants with posttraumatic symptoms. Theory-driven computations were complemented by the novel use of network metrics, which revealed reduced global centrality and higher efficiency within the default mode network for participants with posttraumatic symptoms. Data-driven methods from other studies revealed associations between functional networks and posttraumatic stress disorder (PTSD) symptoms and clusters of functional activation corresponding to different PTSD presentations.

Keywords: PTSD; fMRI; functional connectivity; network models; resting-state.

Publication types

  • Review

MeSH terms

  • Connectome*
  • Humans
  • Magnetic Resonance Imaging
  • Models, Neurological*
  • Neural Networks, Computer*
  • Stress Disorders, Post-Traumatic / diagnostic imaging
  • Stress Disorders, Post-Traumatic / physiopathology*