Influence of beam quality on reference dosimetry correction factors in magnetic resonance guided radiation therapy

Phys Imaging Radiat Oncol. 2020 Oct 27:16:95-98. doi: 10.1016/j.phro.2020.10.005. eCollection 2020 Oct.

Abstract

Correction factors for reference dosimetry in magnetic resonance (MR) imaging-guided radiation therapy ( k B , M , Q ) are often determined in setups that combine a conventional 6 MV linac with an electromagnet. This study investigated whether results based on these measurements were applicable for a 7 MV MR-linac using Monte Carlo simulations. For a Farmer-type ionization chamber, k B , M , Q was assessed for different tissue-phantom ratios ( TPR 20 , 10 ). k B , M , Q differed by 0.0029 ( 43 ) between TPR 20 , 10 = 0.6790 ( 23 ) (6 MV linac) and TPR 20 , 10 = 0.7028 ( 14 ) (7 MV MR-linac) at 1.5 T . The agreement was best in an orientation in which the secondary electrons were deflected to the stem of the ionization chamber.

Keywords: Dosimetry; EGSnrc; Ionization chambers; MR-linac; Magnetic field correction factors; Monte Carlo.