Disseminated cryptococcal infection in an immunocompetent patient treated with short course induction therapy

Alice Parry; Richard Doxey; Rachel Herbert; Ian Moonsie; Neil Stone

doi:10.1016/j.mmcr.2020.12.001

Disseminated cryptococcal infection in an immunocompetent patient treated with short course induction therapy

Med Mycol Case Rep. 2020 Dec 24:32:1-3. doi: 10.1016/j.mmcr.2020.12.001. eCollection 2021 Jun.

Authors

Alice Parry¹, Richard Doxey¹, Rachel Herbert², Ian Moonsie³, Neil Stone⁴

Affiliations

¹ Department of General Medicine, North Middlesex University Hospital, London, UK.
² Department of Microbiology, North Middlesex University Hospital, London, UK.
³ Department of Respiratory Medicine, North Middlesex University Hospital, London, UK.
⁴ Department of Infectious Diseases, University College London Hospital, London, UK.

Abstract

A 49- year old immunocompetent male presented with a right flank abscess and was found to have disseminated cryptococcal disease. Treatment was initiated with a one-week intravenous regime of amphotericin B and flucytosine based on recent trial data that this is as effective, and less toxic, than the standard two weeks. After completion of intravenous treatment he was discharged with oral anti-fungals and is making a good recovery with ongoing follow up.

Keywords: Disseminated cryptococcosis; Immunocompetent; Short course induction therapy.

Publication types

Case Reports