SARS-CoV-2 (COVID-19) and the Endocrine System

Michelle D Lundholm; Caroline Poku; Nicholas Emanuele; Mary Ann Emanuele; Norma Lopez

doi:10.1210/jendso/bvaa144

SARS-CoV-2 (COVID-19) and the Endocrine System

J Endocr Soc. 2020 Oct 1;4(11):bvaa144. doi: 10.1210/jendso/bvaa144. eCollection 2020 Nov 1.

Authors

Michelle D Lundholm¹, Caroline Poku², Nicholas Emanuele^{2

3}, Mary Ann Emanuele², Norma Lopez²

Affiliations

¹ Department of Internal Medicine, Loyola University Medical Center, Maywood, Illinois.
² Department of Medicine, Division of Endocrinology, Loyola University Health Care System, Maywood, Illinois.
³ Endocrinology Section, Medical Service, VA Hospital, Hines, Illinois.

Abstract

As SARS-CoV-2 (COVID-19) overtakes the world, causing moderate to severe disease in about 15% of infected patients, COVID-19 is also found to have widespread effects throughout the body with a myriad of clinical manifestations including the endocrine system. This manuscript reviews what is known about the impact of COVID-19 on the pathophysiology and management of diabetes (both outpatient and inpatient) as well as pituitary, adrenal, thyroid, bone, and gonadal function. Findings in this area are evolving, and long-term effects of infection remain an active area of further research.

Keywords: COVID-19; adrenal; diabetes mellitus; gonads; thyroid diseases.

Publication types

Review