Suitability of low-dose, open food challenge data to supplement double-blind, placebo-controlled data in generation of food allergen threshold dose distributions

Clin Exp Allergy. 2021 Jan;51(1):151-154. doi: 10.1111/cea.13753. Epub 2020 Oct 24.

Authors

Benjamin C Remington¹, Joost Westerhout¹, Anthony E J Dubois², W Marty Blom¹, Astrid G Kruizinga¹, Steve L Taylor³, Geert F Houben¹, Joseph L Baumert³

Affiliations

¹ The Netherlands Organisation for Applied Scientific Research TNO, Utrecht, The Netherlands.
² University Medical Centre Groningen, Groningen, The Netherlands.
³ Food Allergy Research and Resource Program, University of Nebraska, Lincoln, NE, USA.

PMID: 33030225
DOI: 10.1111/cea.13753

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Allergens / administration & dosage
Allergens / adverse effects*
Allergens / immunology
Child
Child, Preschool
Corylus / immunology
Dose-Response Relationship, Immunologic*
Double-Blind Method
Egg Hypersensitivity / etiology
Egg Hypersensitivity / immunology
Female
Food Hypersensitivity / etiology*
Food Hypersensitivity / immunology
Humans
Infant
Information Storage and Retrieval
Male
Milk Hypersensitivity / etiology
Milk Hypersensitivity / immunology
Nut Hypersensitivity / etiology
Nut Hypersensitivity / immunology
Peanut Hypersensitivity / etiology
Peanut Hypersensitivity / immunology
Placebos
Risk Management

Substances

Allergens
Placebos