Multiplexed endoscopic imaging of Barrett's neoplasia using targeted fluorescent heptapeptides in a phase 1 proof-of-concept study

Gut. 2021 Jun;70(6):1010-1013. doi: 10.1136/gutjnl-2020-322945. Epub 2020 Oct 7.
No abstract available

Keywords: Barrett's oesophagus; clinical trials; fluorescence endoscopy; imaging; peptides.

Publication types

  • Clinical Trial, Phase I
  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Aged, 80 and over
  • Barrett Esophagus / diagnostic imaging*
  • Carbocyanines
  • ErbB Receptors
  • Esophagoscopy / methods*
  • False Positive Reactions
  • Female
  • Fluorescent Dyes
  • Humans
  • Indoles
  • Male
  • Middle Aged
  • Molecular Imaging / methods*
  • Peptides
  • Pilot Projects
  • Proof of Concept Study
  • Receptor, ErbB-2

Substances

  • Carbocyanines
  • Fluorescent Dyes
  • IRDye800
  • Indoles
  • Peptides
  • cyanine dye 5
  • EGFR protein, human
  • ERBB2 protein, human
  • ErbB Receptors
  • Receptor, ErbB-2