Macrolide-resistant Bordetella pertussis emerged in Vietnam during 2016-2017. Direct analyses of swab samples from 10 patients with pertussis revealed a macrolide-resistant mutation, A2047G, in the 23S rRNA. We identified the MT104 genotype of macrolide-resistant B. pertussis (which is prevalent in mainland China) and its variants in these patients.
Keywords: 23S rRNA; A2047G mutation; Bordetella pertussis; Vietnam; antimicrobial resistance; bacteria; genotyping; macrolide resistance; respiratory infections.