Antepartum infections are a significant contributor to maternal and fetal morbidity and mortality. Populations in countries with developing economies bear the brunt of the burden of these infections. However, a growing distrust of the medical establishment and vaccination skepticism in wealthier countries has resulted in a resurgence of many of these preventable infections. Understanding these infections and their manifestations is critical not only for diagnosis and management but also for the provision of anticipatory care and guidance to pregnant patients and their families. The following is a discussion of vertically-transmitted antepartum infections, infections that affect the maternal uterus and birth canal, and infections that disproportionately affect pregnant women. While this review only discusses those classes of infections in detail, it is vital to note that any infection present in the general population can present in a pregnant patient and consequently impact the pregnancy.
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