Incidence of Pelvic Inflammatory Disease Associated With Mycoplasma genitalium Infection: Evidence Synthesis of Cohort Study Data

Joanna Lewis; Paddy J Horner; Peter J White

doi:10.1093/cid/ciaa419

Incidence of Pelvic Inflammatory Disease Associated With Mycoplasma genitalium Infection: Evidence Synthesis of Cohort Study Data

Clin Infect Dis. 2020 Dec 17;71(10):2719-2722. doi: 10.1093/cid/ciaa419.

Authors

Joanna Lewis^{1

2}, Paddy J Horner^{3

4}, Peter J White^{1

5}

Affiliations

¹ National Institute for Health Research Health Protection Research Unit in Modelling Methodology and Medical Research Council Centre for Global Infectious Disease Analysis, Imperial College London School of Public Health, London, United Kingdom.
² Centre for Applied Statistics Courses, UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
³ National Institute for Health Research Health Protection Research Unit in Evaluation of Interventions, University of Bristol, Bristol, United Kingdom.
⁴ Population Health Sciences, University of Bristol, Bristol, United Kingdom.
⁵ Modelling and Economics Unit, National Infection Service, Public Health England, London, United Kingdom.

Abstract

We synthesized evidence from the POPI sexual-health cohort study and estimated that 4.9% (95% credible interval, .4-14.1%) of Mycoplasma genitalium infections in women progress to pelvic inflammatory disease versus 14.4% (5.9-24.6%) of chlamydial infections. For validation, we predicted PID rates in 4 age groups that agree well with surveillance data.

Keywords: Mycoplasma genitalium; evidence synthesis; pelvic inflammatory disease; population attributable fraction.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cohort Studies
Female
Humans
Incidence
Mycoplasma Infections* / epidemiology
Mycoplasma genitalium*
Pelvic Inflammatory Disease* / epidemiology

Abstract

Publication types

MeSH terms

Grants and funding