Emergence of a prominent myeloid clone in a ZNF384-rearranged B-cell precursor acute lymphoblastic leukaemia post-corticosteroid pre-phase therapy

Pediatr Blood Cancer. 2020 Dec;67(12):e28513. doi: 10.1002/pbc.28513. Epub 2020 Jul 19.

Authors

Alpeshkumar Bipinbhai Kapadia¹, Sreejesh Sreedharanunni¹, Safal Muhammed², Indrani Karmakar¹, Sonia Rana¹, Prashant Sharma¹, Man Updesh Singh Sachdeva¹, Amita Trehan²

Affiliations

¹ Department of Haematology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
² Unit of Paediatric Haemato-oncology, Department of Paediatrics, Advanced Paediatric Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

PMID: 32686312
DOI: 10.1002/pbc.28513

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adrenal Cortex Hormones / adverse effects*
Blast Crisis / chemically induced
Blast Crisis / pathology*
Child, Preschool
Female
Gene Rearrangement*
Humans
Myeloid Cells / drug effects
Myeloid Cells / pathology*
Oncogene Proteins, Fusion / genetics*
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / genetics
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / pathology
Prognosis

Substances

Adrenal Cortex Hormones
Oncogene Proteins, Fusion
TCF3-ZNF384 fusion protein, human