Cancer-Type-Specific Bacteria: Freeloaders or Partners?

K Leigh Greathouse; Joshua K Stone; Curtis C Harris

doi:10.1016/j.ccell.2020.06.017

Cancer-Type-Specific Bacteria: Freeloaders or Partners?

Cancer Cell. 2020 Aug 10;38(2):158-160. doi: 10.1016/j.ccell.2020.06.017. Epub 2020 Jul 9.

Authors

K Leigh Greathouse¹, Joshua K Stone², Curtis C Harris³

Affiliations

¹ Human Science and Design, Robbins College of Health and Human Sciences, Baylor University, Waco, TX, USA.
² Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
³ Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA. Electronic address: harrisc@mail.nih.gov.

PMID: 32649886
DOI: 10.1016/j.ccell.2020.06.017

Abstract

A paper published in Science probes over 1500 tumor samples from multiple cancer types for markers of a tumor microbiome and viable bacteria. Unique intertumoral and intracellular signatures associated with clinical biomarkers and metabolic pathways provide clues to the roles bacteria play in carcinogenesis.

Publication types

Comment

MeSH terms

Bacteria / genetics
Carcinogenesis
Humans
Microbiota*
Neoplasms*