Unintended on-target chromosomal instability following CRISPR/Cas9 single gene targeting
Ann Oncol
.
2020 Sep;31(9):1270-1273.
doi: 10.1016/j.annonc.2020.04.480.
Epub 2020 May 15.
Authors
J Przewrocka
1
,
A Rowan
2
,
R Rosenthal
2
,
N Kanu
3
,
C Swanton
4
Affiliations
1
The Francis Crick Institute, London, UK; University College London, London, UK.
2
The Francis Crick Institute, London, UK.
3
University College London, London, UK.
4
The Francis Crick Institute, London, UK; University College London, London, UK. Electronic address: charles.swanton@crick.ac.uk.
PMID:
32422169
PMCID:
PMC7487774
DOI:
10.1016/j.annonc.2020.04.480
No abstract available
Publication types
Letter
Research Support, Non-U.S. Gov't
MeSH terms
CRISPR-Cas Systems*
Chromosomal Instability
Gene Targeting*
Humans
Grants and funding
FC001169/MRC_/Medical Research Council/United Kingdom
FC001169/WT_/Wellcome Trust/United Kingdom
FC001169/CRUK_/Cancer Research UK/United Kingdom