First molecular analysis of rabies virus in Qatar and clinical cases imported into Qatar, a case report

Bas B Oude Munnink; Elmoubashar Abu Baker Abd Farag; Corine GeurtsvanKessel; Claudia Schapendonk; Anne van der Linden; Robert Kohl; Georgina Arron; Hisham Ziglam; Wael Goravey Mhjoop Goravey; Peter V Coyle; Imad Ibrahim; Khaled A Mohran; Muneera Mohammed Saleh Alrajhi; Md Mazharul Islam; Randa Abdeen; A Aziz Mahmoud A H Al-Zeyara; Nidal Mahmoud Younis; Hamad Eid Al-Romaihi; Mohammad Hamad J Al Thani; Richard Molenkamp; Reina S Sikkema; Marion Koopmans

doi:10.1016/j.ijid.2020.04.070

First molecular analysis of rabies virus in Qatar and clinical cases imported into Qatar, a case report

Int J Infect Dis. 2020 Jul:96:323-326. doi: 10.1016/j.ijid.2020.04.070. Epub 2020 May 4.

Authors

Bas B Oude Munnink¹, Elmoubashar Abu Baker Abd Farag², Corine GeurtsvanKessel¹, Claudia Schapendonk¹, Anne van der Linden¹, Robert Kohl¹, Georgina Arron¹, Hisham Ziglam³, Wael Goravey Mhjoop Goravey³, Peter V Coyle³, Imad Ibrahim³, Khaled A Mohran⁴, Muneera Mohammed Saleh Alrajhi⁵, Md Mazharul Islam⁵, Randa Abdeen⁵, A Aziz Mahmoud A H Al-Zeyara⁵, Nidal Mahmoud Younis⁵, Hamad Eid Al-Romaihi², Mohammad Hamad J Al Thani², Richard Molenkamp¹, Reina S Sikkema¹, Marion Koopmans¹

Affiliations

¹ Erasmus MC, Department of Viroscience, WHO collaborating centre for arbovirus and viral hemorrhagic fever Reference and Research, Rotterdam, the Netherlands.
² Ministry of Public of Health, Doha, Qatar.
³ Hamad Medical Corporation, Doha, Qatar.
⁴ Department of Animal Resources, Ministry of Municipals and Environment, Doha, Qatar; Animal Health Research Institute, Biotechnology Departments ERC, Dokki, Egypt.
⁵ Department of Animal Resources, Ministry of Municipals and Environment, Doha, Qatar.

PMID: 32376305
DOI: 10.1016/j.ijid.2020.04.070

Abstract

Identifying the origin of the rabies virus (RABV) infection may have significant implications for control measures. Here, we identified the source of a RABV infection of two Nepalese migrants in Qatar by comparing their RABV genomes with RABV genomes isolated from the brains of a RABV infected camel and fox from Qatar.

Keywords: Nanopore sequencing; metagenomic sequencing; rabies virus.

Publication types

Case Reports

MeSH terms

Adult
Animals
Brain / virology
Camelus
Foxes
Genome, Viral
Humans
Male
Qatar
Rabies / veterinary
Rabies / virology*
Rabies virus / genetics*
Rabies virus / isolation & purification