A Genome Assembly of the Barley 'Transformation Reference' Cultivar Golden Promise

G3 (Bethesda). 2020 Jun 1;10(6):1823-1827. doi: 10.1534/g3.119.401010.

Abstract

Barley (Hordeum vulgare) is one of the most important crops worldwide and is also considered a research model for the large-genome small grain temperate cereals. Despite genomic resources improving all the time, they are limited for the cv Golden Promise, the most efficient genotype for genetic transformation. We have developed a barley cv Golden Promise reference assembly integrating Illumina paired-end reads, long mate-pair reads, Dovetail Chicago in vitro proximity ligation libraries and chromosome conformation capture sequencing (Hi-C) libraries into a contiguous reference assembly. The assembled genome of 7 chromosomes and 4.13Gb in size, has a super-scaffold N50 after Chicago libraries of 4.14Mb and contains only 2.2% gaps. Using BUSCO (benchmarking universal single copy orthologous genes) as evaluation the genome assembly contains 95.2% of complete and single copy genes from the plant database. A high-quality Golden Promise reference assembly will be useful and utilized by the whole barley research community but will prove particularly useful for CRISPR-Cas9 experiments.

Keywords: Barley; Golden Promise; reference assembly.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genome
  • Genomics
  • Genotype
  • High-Throughput Nucleotide Sequencing
  • Hordeum* / genetics

Associated data

  • figshare/10.6084/m9.figshare.9332045