IL-1β and IL-17A are involved in IVIG resistance through activation of C/EBPβ and δ in a coronary artery model of Kawasaki disease

Allergy. 2020 Aug;75(8):2102-2105. doi: 10.1111/all.14281. Epub 2020 Apr 6.

Authors

Takashi Inoue^{1

2}, Masaki Miyashita¹, Shokei Murakami^{1

3}, Arisa Igarashi¹, Kenichiro Motomura¹, Jun Abe⁴, Kenji Matsumoto¹, Akio Matsuda¹

Affiliations

¹ Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Tokyo, Japan.
² Department of Pediatrics, Jikei University School of Medicine, Tokyo, Japan.
³ Department of Pediatrics, Toyama University School of Medicine, Toyama, Japan.
⁴ Department of Advanced Medicine for Infections, National Research Institute for Child Health and Development, Tokyo, Japan.

PMID: 32187376
DOI: 10.1111/all.14281

No abstract available

Keywords: C/EBP; IL-17A; IL-1β; IVIG; Kawasaki disease.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

CCAAT-Enhancer-Binding Protein-beta
Coronary Artery Disease*
Coronary Vessels / diagnostic imaging
Humans
Immunoglobulins, Intravenous / therapeutic use
Interleukin-17
Interleukin-1beta
Mucocutaneous Lymph Node Syndrome* / drug therapy

Substances

CCAAT-Enhancer-Binding Protein-beta
IL1B protein, human
Immunoglobulins, Intravenous
Interleukin-17
Interleukin-1beta