[Management strategies for three patients with gynecological malignancies during the outbreak of COVID-19]

Zhonghua Fu Chan Ke Za Zhi. 2020 Apr 25;55(4):221-226. doi: 10.3760/cma.j.cn112141-20200302-00168.
[Article in Chinese]

Abstract

Objective: To explore the management strategies for patients with gynecological malignant tumors during the outbreak and transmission of COVID-19. Methods: We retrospectively analyzed the clinical characteristics, treatment, and disease outcomes of three patients with gynecological malignancies associated with COVID-19 in Renmin Hospital of Wuhan University, and proposed management strategies for patients with gynecological tumors underriskof COVID-19. Results: Based on the national diagnosis and treatment protocol as well as research progress for COVID-19, three patients with COVID-19 were treated. Meanwhile, they were also appropriately adjusted the treatment plan in accordance with the clinical guidelines for gynecological tumors. Pneumonia was cured in 2 patients, and one patient died of COVID-19. Conclusions: Patients with gynecological malignant tumors are high-risk groups prone to COVID-19, and gynecological oncologists need to carry out education, prevention, control and treatment according to specific conditions. While, actively preventing and controlling COVID-19, the diagnosis and treatment of gynecological malignant tumors should be carried out in an orderly and safe manner.

目的: 在新型冠状病毒肺炎(COVID-19)暴发和传播期间,探讨妇科恶性肿瘤患者的管理策略。 方法: 回顾性分析2020年1月1日—2020年3月12日武汉大学人民医院收治的3例妇科恶性肿瘤伴COVID-19患者的临床特点、处理方案和疾病转归,提出COVID-19流行期间妇科恶性肿瘤患者的管理策略。 结果: 3例妇科恶性肿瘤伴COVID-19患者,在按照国家颁布的COVID-19诊治方案及研究进展给予针对性治疗的前提下,依照妇科恶性肿瘤临床指南适当调整治疗策略,先行COVID-19治疗,改用妇科恶性肿瘤的其他备选治疗方案,对肿瘤进行个体化的治疗。3例妇科恶性肿瘤伴COVID-19患者中,2例COVID-19治愈,择期行肿瘤治疗;1例因COVID-19病情进展迅速,死于呼吸循环衰竭。 结论: 妇科恶性肿瘤患者是感染COVID-19的高危人群,妇科肿瘤医师需根据具体情况做好宣教、防控及治疗等工作。在积极防控COVID-19的同时,有序、安全地开展妇科恶性肿瘤患者的诊治。.

Keywords: COVID-19; Coronavirus infections; Cross infection; Genital neoplasms, female; Infection control; Patient care management.

MeSH terms

  • Betacoronavirus
  • COVID-19
  • COVID-19 Testing
  • Clinical Laboratory Techniques
  • Coronavirus Infections / complications*
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / mortality
  • Disease Management
  • Disease Outbreaks / prevention & control
  • Female
  • Genital Neoplasms, Female / diagnosis
  • Genital Neoplasms, Female / surgery*
  • Humans
  • Pandemics* / prevention & control
  • Patient Care Planning
  • Pneumonia, Viral / complications*
  • Pneumonia, Viral / epidemiology
  • Pneumonia, Viral / mortality
  • Retrospective Studies
  • Risk
  • SARS-CoV-2