Concomitant 1p/19q co-deletion and IDH1/2, ATRX, and TP53 mutations within a single clone of "dual-genotype" IDH-mutant infiltrating gliomas

Acta Neuropathol. 2020 Jun;139(6):1105-1107. doi: 10.1007/s00401-020-02141-x. Epub 2020 Mar 13.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / genetics
  • Genotype
  • Glioma / diagnosis
  • Glioma / genetics*
  • Humans
  • Isocitrate Dehydrogenase / genetics*
  • Male
  • Middle Aged
  • Mutation / genetics
  • Tumor Suppressor Protein p53 / genetics*
  • X-linked Nuclear Protein / genetics*

Substances

  • TP53 protein, human
  • Tumor Suppressor Protein p53
  • Isocitrate Dehydrogenase
  • IDH1 protein, human
  • ATRX protein, human
  • X-linked Nuclear Protein