We report the first documented case of hepatitis E virus-associated haemophagocytic lymphohistiocytosis. This case emphasizes the fact that infectious agents other than those classically described should be taken into consideration as a potential trigger of virus-associated haemophagocytic syndrome. Prompt recognition is crucial to start early treatment of the underlying infection and possibly improve the outcome of this frequently fatal syndrome.
Keywords: Hepatitis E Virus; central Nerve System Infection; haemophagocytic lymphohistiocytosis; virus-associated Haemophagocytic Syndrome.