Assessment of clinical outcomes and histomorphometric findings in alveolar ridge augmentation procedures with allogeneic bone block grafts: A systematic review and meta-analysis

Med Oral Patol Oral Cir Bucal. 2020 Mar 1;25(2):e291-e298. doi: 10.4317/medoral.23353.

Abstract

Background: This systematic literature review aimed to evaluate the efficacy of allogeneic bone blocks for ridge augmentation by assessing block survival rates and subsequent implant survival, including post-surgical complications and histomorphometric analysis.

Material and methods: An electronic and manual search among references, was conducted up to April 2019 by two independent authors. Inclusion criteria were: human clinical trials in which the outcomes of allogeneic bone block grafts were evaluated by means of their survival rates and subsequent implant success rates.

Results: Seven articles fulfilled the inclusion criteria and were analyzed. A total of 323 allogeneic block grafts were monitored for a minimum of 12 months follow-up after surgery, of which thirteen (4.02%) failed. Regarding the cumulative implant survival rate, the weighted mean was 97.36%, computed from 501 implants. Histologic and histomorphometric analysis showed that allogeneic block grafts presented some clinical and microstructural differences in comparison with autologous block grafts.

Conclusions: Atrophic alveolar crest reconstruction with allogeneic bone block grafts would appear a feasible alternative to autologous bone block grafts, obtaining a low block graft failure rate, similar implant survival rate and fewer postoperative complications. Further investigations generating long term data are needed to confirm these findings.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Alveolar Ridge Augmentation*
  • Atrophy
  • Bone Transplantation
  • Dental Implantation, Endosseous
  • Dental Implants*
  • Hematopoietic Stem Cell Transplantation*
  • Humans

Substances

  • Dental Implants