Rare Loss-of-Function Mutation in SERPINA3 in Generalized Pustular Psoriasis

Affiliations

• ¹ Department of Internal Medicine 3 - Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
• ² Bioinformatics, Institute of Biochemistry, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
• ³ Department of Dermatology, University of Bonn, Bonn, Germany.
• ⁴ Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
• ⁵ Department of Medicine 1, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
• ⁶ Department of Radiation Oncology, Universitätsklinikum Erlangen, Erlangen, Germany.
• ⁷ Division of Rheumatology and IME, Fraunhofer Project Group Translational Medicine and Pharmacology, Goethe University, Frankfurt am Main, Germany.
• ⁸ Department of Internal Medicine I, José-Carreras Centrum for Immuno- and Gene Therapy, University of Saarland Medical School, Homburg/Saar, Germany.
• ⁹ Department of Dermatology, Dermatology Clinic, University of Tartu, Tartu, Estonia.
• ¹⁰ Department of Pathophysiology, University of Tartu, Tartu, Estonia; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University and The Perron Institute for Neurological and Translational Science, Perth, Western Australia, Australia.
• ¹¹ Department of Dermatology, Georg-August-University Göttingen, Göttingen, Germany.
• ¹² Department of Dermatology and Allergology; Ludwig-Maximilian University Munich, Munich, Germany.
• ¹³ Department of Dermatology, University of Münster, Münster, Germany.
• ¹⁴ Department of Dermatology, Fachklinik Bad Bentheim, Bad Bentheim, Germany.
• ¹⁵ Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany. Electronic address: Ulrike.Hueffmeier@uk-erlangen.de.