Objective: To observe the volume and distribution of necrotic tissue of femoral head in steroid-induced osteonecrosis of femoral head (SONFH) patients by three-dimensional reconstruction of CT.
Methods: A clinical data of 25 patients with SONFH between September 2016 and December 2018 was analyzed. There were 22 males and 3 females, with an average age of 38.8 years (range, 20-63 years). The necrosis of the femoral head was in stage Ⅱ of Association Research Circulation Osseous (ARCO). The disease duration ranged from 3 to 18 months, with an average of 9.2 months. A three-dimensional reconstruction with CT data of SONFH patients were performed by Mimics Research 21.0 software and the femoral head was segmented into eight regions by 3-matic Research 13.0 software. The volume of necrotic tissue of the femoral head and the volume rate of necrotic tissue to femoral head were calculated and the distribution was also analyzed.
Results: The three-dimensional digital model of the femoral head showed that the necrotic tissue of the femoral head was located above the anterior superior medial, and the area of the necrotic tissue was in a dome-like shape. The results showed that the necrotic tissue in the femoral head was mainly concentrated on the anterior superior internal area, the anterior superior outer area, and the posterior superior internal area. The volume of femoral head was (48 399.52±9 408.90) mm 3, and the volume of necrotic tissue was (20 917.08±6 566.94) mm 3, and the volume ratio of necrotic tissue to femoral head was 44.75%±15.72%. The proportion of necrotic volume in different regions was different, and the necrotic tissues were mainly distributed in the anterior superior internal area, the anterior superior outer area, and the posterior superior internal area.
Conclusion: The volume and distribution of necrotic tissue in femoral head can be evaluated quickly and intuitively by three-dimensional reconstruction of CT in Mimics software.
目的: 利用 CT 三维重建观察激素性股骨头坏死患者股骨头坏死组织体积及分布情况。.
方法: 以 2016 年 9 月—2018 年 12 月收治并符合选择标准的 25 例激素性股骨头坏死患者为研究对象。男 22 例，女 3 例；年龄 20～63 岁，平均 38.8 岁。股骨头坏死均为国际骨循环研究会（ARCO）Ⅱ期；病程 3～18 个月，平均 9.2 个月。首先行髋关节 CT 扫描，采用 Mimics Research 21.0 软件三维重建股骨头并识别坏死组织；然后利用 3-matic Research 13.0 软件将重建的股骨头分割为 8 个区域，测算股骨头、坏死组织体积，坏死组织体积比，以及不同区域坏死组织分布情况。.
结果: 股骨头三维数字模型显示坏死组织主要位于股骨头前上方，坏死组织区域主要呈穹窿状。股骨头分区显示坏死组织主要集中于前上内区、前上外区与后上内区。25 例患者股骨头体积为（48 399.52±9 408.90）mm 3，坏死组织体积为（20 917.08±6 566.94）mm 3，坏死组织体积比为 44.75%±15.72%。不同区域坏死组织体积及体积比不一致，其中前上内区、前上外区和后上内区较大。.
结论: 基于 CT 三维重建能快速直观地评估股骨头坏死组织体积及分布情况。.
Keywords: Mimics software; Steroid induced osteonecrosis of femoral head; distribution; three-dimensional reconstruction.