Double hit B cell precursor leukemia/lymphoma in a patient with a prior diagnosis of follicular lymphoma: a diagnostic and therapeutic dilemma

Ann Hematol. 2020 Feb;99(2):391-393. doi: 10.1007/s00277-019-03897-3. Epub 2019 Dec 20.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Abnormal Karyotype
  • Antigens, Neoplasm / analysis
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Asparaginase / administration & dosage
  • Biomarkers, Tumor / analysis
  • Biopsy
  • Cyclophosphamide / administration & dosage
  • DNA Nucleotidylexotransferase / analysis
  • Disease Progression
  • Doxorubicin / administration & dosage
  • Fatal Outcome
  • Female
  • Humans
  • Lymphoma, Follicular / drug therapy
  • Lymphoma, Follicular / pathology*
  • Mercaptopurine / administration & dosage
  • Methotrexate / administration & dosage
  • Middle Aged
  • Pancytopenia / etiology
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / diagnosis
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / etiology*
  • Prednisone / administration & dosage
  • Recurrence
  • Rituximab / administration & dosage
  • Salvage Therapy
  • Splenic Rupture / etiology
  • Splenomegaly / etiology
  • Stomach / pathology
  • Vincristine / administration & dosage

Substances

  • Antigens, Neoplasm
  • Biomarkers, Tumor
  • Rituximab
  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Mercaptopurine
  • DNA Nucleotidylexotransferase
  • Asparaginase
  • Prednisone
  • Methotrexate

Supplementary concepts

  • CCG-141 protocol
  • CHOP protocol