Intracranial Stenting: Is It Still an Option for Treatment of Patients With Intracranial Atherosclerosis?

Ahmed Abualhasan; Foad Abd-Allah; Guglielmo Pero; Khaled Sobh; Ossama Mansour; Omar El-Serafy; Edoardo Boccardi

doi:10.3389/fneur.2019.01248

Intracranial Stenting: Is It Still an Option for Treatment of Patients With Intracranial Atherosclerosis?

Front Neurol. 2019 Nov 22:10:1248. doi: 10.3389/fneur.2019.01248. eCollection 2019.

Authors

Ahmed Abualhasan^{1

2}, Foad Abd-Allah¹, Guglielmo Pero², Khaled Sobh³, Ossama Mansour⁴, Omar El-Serafy¹, Edoardo Boccardi²

Affiliations

¹ Department of Neurology, Faculty of Medicine, Cairo University, Cairo, Egypt.
² Department of Neuroradiology, Ospedale Niguarda Ca' Granda, Milan, Italy.
³ Department of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
⁴ Department of Neurology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

Abstract

Intracranial atherosclerotic disease (ICAD) is considered a major cause of recurrent cerebrovascular events. ICAD continues to be a disease without an effective method of reducing the risk of recurrent stroke and death, even with aggressive, highly monitored medical treatment. We reviewed data from three randomized controlled studies that published data comparing intracranial stenting vs. medical treatment for symptomatic severe-ICAD. Ethnic, demographic, clinical, and procedural differences were observed among the data from these trials that might influence their results. Future research should aim at establishing refined selection criteria that can identify high-risk ICAD patients who may benefit from intracranial stenting.

Keywords: angioplasty; endovascular treatment; intracranial atherosclerosis; intracranial stenting; medical therapy; stroke.

Publication types

Review