Evidence-Based Minireview: Longitudinal geriatric assessment in quality care for older patients with hematologic malignancies

Hematology Am Soc Hematol Educ Program. 2019 Dec 6;2019(1):59-62. doi: 10.1182/hematology.2019000076.

Abstract

A 65-year-old women was diagnosed with acute myeloid leukemia (AML; normal cytogenetics, NPM1 mutated, FLT3-ITD wild type). Preinduction screening geriatric assessment (GA) did not reveal any significant deficit, because she was independent of basic activities of daily living (ADLs) and instrumental activities of daily living (IADLs), had normal cognition, and scored 10 (range 0-12) on the short physical performance battery (SPPB). She underwent standard 7 + 3 induction and achieved a complete remission, although her course was complicated by neutropenic sepsis and bacteremia. She is being evaluated for postremission therapy. Would you recommend a follow-up GA at this time?

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aged
  • Geriatric Assessment*
  • Hematologic Neoplasms / therapy*
  • Hematopoietic Stem Cell Transplantation
  • Humans
  • Longitudinal Studies
  • Nucleophosmin
  • Observational Studies as Topic
  • Quality of Health Care*
  • Quality of Life