Multiple cytokine-producing aggressive EBV-positive diffuse large B cell lymphoma, not otherwise specified with hemophagocytic syndrome

Ann Hematol. 2020 Feb;99(2):381-383. doi: 10.1007/s00277-019-03849-x. Epub 2019 Nov 25.

Affiliations

¹ Division of Hematology and Rheumatology, Faculty of Medicine, Kindai University, 377-2, Ono-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan. s.nakayama@med.kindai.ac.jp.
² Division of Hematology and Rheumatology, Faculty of Medicine, Kindai University, 377-2, Ono-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan.

PMID: 31768673
DOI: 10.1007/s00277-019-03849-x

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Antineoplastic Combined Chemotherapy Protocols / administration & dosage
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Bone Marrow / pathology
Cyclophosphamide / administration & dosage
Cytokines / analysis
Cytokines / biosynthesis*
Doxorubicin / administration & dosage
Epstein-Barr Virus Infections / complications*
Epstein-Barr Virus Infections / metabolism
Fatal Outcome
Female
Herpesvirus 4, Human / isolation & purification*
Humans
Lymph Nodes / pathology
Lymphohistiocytosis, Hemophagocytic / etiology*
Lymphohistiocytosis, Hemophagocytic / pathology
Lymphoma, Large B-Cell, Diffuse / complications*
Lymphoma, Large B-Cell, Diffuse / drug therapy
Lymphoma, Large B-Cell, Diffuse / metabolism
Lymphoma, Large B-Cell, Diffuse / virology
Middle Aged
Neoplastic Stem Cells / chemistry
Neoplastic Stem Cells / pathology
Neoplastic Stem Cells / virology*
Prednisone / administration & dosage
RNA, Viral / analysis
Rituximab / administration & dosage
Vincristine / administration & dosage

Substances

Cytokines
RNA, Viral
Rituximab
Vincristine
Doxorubicin
Cyclophosphamide
Prednisone

Supplementary concepts

CHOP protocol